Arthritis is inflammation of one or more of your joints. The main symptoms of arthritis are joint pain and stiffness, which typically worsen with age. The most common types of arthritis are osteoarthritis and rheumatoid arthritis What are the early signs of arthritis? Early Signs of Rheumatoid Arthritis Fatigue You may feel unusually tired well before any other symptoms become obvious. Fatigue can come before the onset of other symptoms by weeks or months. It may come and go from week to week or day to day. Fatigue is sometimes accompanied by a general feeling of ill health or even depression. Morning stiffness Morning stiffness is often an early sign of arthritis. Stiffness that lasts for a few minutes is usually a symptom of a form of arthritis that can worsen over time without proper treatment. Stiffness that lasts for several hours is generally a symptom of inflammatory arthritis and is typical of RA. You may also feel stiffness after a